Etifoxine hydrochloride

CAS No. 56776-32-0

Etifoxine hydrochloride ( HOE 36-801 hydrochloride )

Catalog No. M22932 CAS No. 56776-32-0

Etifoxine is an anxiolytic and anticonvulsant drug.?Unlike benzodiazepines, etifoxine appears to produce its anxiolytic effects by binding to β2 and β3 subunits of the GABAA receptor complex, and so is acting at a different target site to benzodiazepines, although the physiological effect that is produced is similar to that of benzodiazepines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 31 In Stock
5MG 50 In Stock
10MG 72 In Stock
25MG 138 In Stock
50MG 250 In Stock
100MG 444 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Etifoxine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Etifoxine is an anxiolytic and anticonvulsant drug.?Unlike benzodiazepines, etifoxine appears to produce its anxiolytic effects by binding to β2 and β3 subunits of the GABAA receptor complex, and so is acting at a different target site to benzodiazepines, although the physiological effect that is produced is similar to that of benzodiazepines.
  • Description
    Etifoxine is an anxiolytic and anticonvulsant drug.?Unlike benzodiazepines, etifoxine appears to produce its anxiolytic effects by binding to β2 and β3 subunits of the GABAA receptor complex, and so is acting at a different target site to benzodiazepines, although the physiological effect that is produced is similar to that of benzodiazepines.
  • Synonyms
    HOE 36-801 hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GABA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    56776-32-0
  • Formula Weight
    337.24
  • Molecular Formula
    C17H18Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (148.26 mM; Need ultrasonic)
  • SMILES
    ClC1=CC=C2C(C(C3=CC=CC=C3)(C)OC(NCC)=N2)=C1.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Verleye M, Dumas S, Heulard I, et al. Differential effects of etifoxine on anxiety-like behaviour and convulsions in BALB/cByJ and C57BL/6J mice: any relation to overexpression of central GABAA receptor beta2 subunits Eur Neuropsychopharmacol. 2011 Jun;21(6):457-70.
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